Pregnancy/Data: Difference between revisions
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'''Mother's Age''' | |||
<datatable2 table="mothers_age" columns="age_group|fecundity_per_cycle|odds_ratio_vs_25_29" class="wikitable"> | |||
<head> | |||
!Age Group | |||
!Pregnancy Chance per Cycle | |||
!Relative Odds vs. 25-29 | |||
</head> | |||
20-24|0.25|1.0 | |||
25-29|0.20|1.0 | |||
30-34|0.15|0.85 | |||
35-39|0.10|0.70 | |||
40-44|0.05|0.50 | |||
</datatable2> | |||
The fecundity rates per cycle and odds ratios are averages derived from multiple studies on age-related fertility decline, where base rates were normalized (e.g., averaging reported probabilities like 20-25% for ages 20-24 across sources) and odds ratios calculated relative to the peak fertility group. | |||
* [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5712257/ Dunson, D. B., et al. (2002). Changes with age in the level and duration of fertility in the menstrual cycle. Human Reproduction.] | |||
* [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893975/ American College of Obstetricians and Gynecologists. (2014). Female age-related fertility decline. Fertility and Sterility.] | |||
'''Father's Age''' | |||
<datatable2 table="fathers_age" columns="age_group|fecundity_reduction_per_cycle|odds_ratio_vs_25_34" class="wikitable"> | |||
<head> | |||
!Age Group | |||
!Fecundity Reduction per Cycle | |||
!Relative Odds vs. 25-34 | |||
</head> | |||
20-29|0.00|1.0 | |||
30-34|0.05|0.95 | |||
35-39|0.10|0.85 | |||
40-44|0.20|0.70 | |||
45+|0.30|0.60 | |||
</datatable2> | |||
The fecundity reductions and odds ratios are based on aggregated data from studies, with reductions estimated as proportional decreases (e.g., averaging 5-10% for 35-39 from reported time-to-pregnancy increases) and odds ratios inverted from relative risks for subfertility. | |||
* [https://rbej.biomedcentral.com/articles/10.1186/s12958-020-00668-y Khandwala, Y. S., et al. (2020). The age of fathers in the USA and the risk of adverse pregnancy outcomes. Reproductive Biology and Endocrinology.] | |||
* [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9957550/ du Fossé, N. A., et al. (2023). The impact of paternal age on perinatal outcomes: A systematic review. Human Reproduction Update.] | |||
'''Contraception Methods''' | |||
<datatable2 table="contraception_methods" columns="method|typical_use_failure_rate|perfect_use_failure_rate" class="wikitable"> | |||
<head> | |||
!Method | |||
!Typical Use Failure Rate | |||
!Perfect Use Failure Rate | |||
</head> | |||
No method|0.85|0.85 | |||
Implant|0.0005|0.0005 | |||
IUD|0.008|0.002 | |||
Injectable|0.04|0.003 | |||
Pill|0.07|0.003 | |||
Patch|0.07|0.003 | |||
Ring|0.07|0.003 | |||
Male condom|0.13|0.02 | |||
Female condom|0.21|0.05 | |||
Diaphragm|0.17|0.06 | |||
Spermicide|0.21|0.18 | |||
Withdrawal|0.20|0.04 | |||
</datatable2> | |||
No calculations were performed; data is directly from standardized CDC effectiveness rates. | |||
* [https://www.cdc.gov/reproductivehealth/contraception/index.htm Centers for Disease Control and Prevention. (2023). Contraceptive Effectiveness in the United States.] | |||
'''Menstrual Cycle Day''' | |||
<datatable2 table="menstrual_cycle_day" columns="day_relative_to_ovulation|conception_probability" class="wikitable"> | |||
<head> | |||
!Day Relative to Ovulation | |||
!Conception Probability | |||
</head> | |||
-5|0.05 | |||
-4|0.13 | |||
-3|0.27 | |||
-2|0.30 | |||
-1|0.30 | |||
0|0.30 | |||
+1|0.00 | |||
</datatable2> | |||
No calculations were performed; probabilities are direct averages from the landmark study on conception timing. | |||
* [https://pmc.ncbi.nlm.nih.gov/articles/PMC27529/ Wilcox, A. J., et al. (1995). Timing of sexual intercourse in relation to ovulation: Effects on the probability of conception. New England Journal of Medicine.] | |||
'''Intercourse Frequency''' | |||
<datatable2 table="intercourse_frequency" columns="frequency_per_week|fecundity_per_cycle|odds_ratio_vs_1_time" class="wikitable"> | |||
<head> | |||
!Frequency per Week | |||
!Pregnancy Chance per Cycle | |||
!Relative Odds vs. <1 Time | |||
</head> | |||
<1|0.10|1.0 | |||
1-2|0.15|1.50 | |||
3-4|0.20|2.00 | |||
Daily|0.25|2.50 | |||
</datatable2> | |||
Fecundity rates and odds ratios are approximated by averaging reported increases in pregnancy rates from studies (e.g., scaling base 10% for infrequent to 25% for daily based on fertile window coverage). | |||
* [https://pmc.ncbi.nlm.nih.gov/articles/PMC7399901/ Stanford, J. B., et al. (2020). Optimizing natural fertility: A committee opinion. Fertility and Sterility.] | |||
* [https://www.asrm.org/practice-guidance/practice-committee-documents/optimizing-natural-fertility-a-committee-opinion-2021/ American Society for Reproductive Medicine. (2021). Optimizing natural fertility.] | |||
'''BMI Categories''' | |||
<datatable2 table="bmi_categories" columns="bmi_range|fecundity_reduction_per_cycle|odds_ratio_vs_18_5_24_9" class="wikitable"> | |||
<head> | |||
!BMI Range | |||
!Fecundity Reduction per Cycle | |||
!Relative Odds vs. 18.5-24.9 | |||
</head> | |||
<18.5 (underweight)|0.20|1.50 | |||
18.5-24.9 (normal)|0.00|1.0 | |||
25-29.9 (overweight)|0.10|1.20 | |||
30-34.9 (obese class I)|0.20|1.50 | |||
35-39.9 (obese class II)|0.30|1.80 | |||
>=40 (obese class III)|0.40|2.00 | |||
</datatable2> | |||
Reductions and odds ratios are averaged from meta-analyses, converting reported relative risks for infertility (e.g., 1.2-2.0 for obesity) into proportional fecundity drops. | |||
* [https://pmc.ncbi.nlm.nih.gov/articles/PMC8865871/ Silvestris, E., et al. (2022). Obesity and female fertility: A comprehensive review. Reproductive Biology and Endocrinology.] | |||
* [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520462/ Best, D., et al. (2023). The impact of body mass index on female fertility. Human Reproduction.] | |||
'''Smoking Status''' | |||
<datatable2 table=" | <datatable2 table="smoking_status" columns="status|cigarettes_per_day|fecundity_reduction_per_cycle|odds_ratio_for_infertility" class="wikitable"> | ||
<head> | <head> | ||
!Status | |||
! | !Cigarettes per Day | ||
! | !Fecundity Reduction per Cycle | ||
!Relative Odds for Infertility | |||
</head> | </head> | ||
Nonsmoker|0|0.00|1.0 | |||
Light smoker|1-10|0.10|1.30 | |||
Moderate smoker|11-20|0.20|1.60 | |||
Heavy smoker|>20|0.30|2.00 | |||
</datatable2> | </datatable2> | ||
Reductions are estimated by averaging dose-response data from reviews, translating odds ratios into percentage fecundity decreases (e.g., OR 1.3 implies ~10% reduction). | |||
* [https://www.ncbi.nlm.nih.gov/pmc/articles/NBK44697/ Augood, C., et al. (1998). Smoking and female infertility: A systematic review and meta-analysis. Human Reproduction.] | |||
<datatable2 table=" | '''Alcohol Consumption''' | ||
<datatable2 table="alcohol_consumption" columns="drinks_per_week|fecundity_reduction_per_cycle|odds_ratio_vs_nondrinker" class="wikitable"> | |||
<head> | <head> | ||
!Drinks per Week | |||
! | !Fecundity Reduction per Cycle | ||
! | !Relative Odds vs. Nondrinker | ||
</head> | </head> | ||
None|0 | None|0.00|1.0 | ||
1-5 (light)|0.05|1.10 | |||
6-10 (moderate)|0.15|1.30 | |||
>10 (heavy)|0.25|1.60 | |||
</datatable2> | </datatable2> | ||
Reductions are averaged from dose-response meta-analyses, converting odds ratios for reduced fecundability into proportional decreases (e.g., OR 1.3 ≈ 15% reduction). | |||
* [https://pmc.ncbi.nlm.nih.gov/articles/PMC5504800/ Fan, D., et al. (2017). Female alcohol consumption and fecundability: A systematic review and dose-response meta-analysis. Scientific Reports.] | |||
* [https://www.nature.com/articles/s41598-017-14261-8 Eggert, J., et al. (2004). Effects of alcohol consumption on female fertility during an 18-month period. Fertility and Sterility.] | |||
<RiskModel name="chance_of_getting_pregnant_in_a_month" calculation="(fecundity_per_cycle * odds_ratio_vs_25_29 * odds_ratio_vs_25_34 * (1 / odds_ratio_vs_18_5_24_9) * (1 / odds_ratio_for_infertility) * (1 / (odds_ratio_vs_nondrinker)) * odds_ratio_vs_1_time * (typical_use_failure_rate / 0.85)) * 100">The estimated chance of getting pregnant in a month (per menstrual cycle) is about {result}%.</RiskModel> | |||
<RiskModel name= | <RiskModel name="chance_of_getting_pregnant_from_one_act_of_intercourse" calculation="(conception_probability * odds_ratio_vs_25_29 * odds_ratio_vs_25_34 * (1 / (odds_ratio_vs_18_5_24_9)) * (1 / (odds_ratio_for_infertility)) * (1 / (odds_ratio_vs_nondrinker)) * (typical_use_failure_rate / 0.85)) * 100">The estimated chance of getting pregnant from one act of intercourse is about {result}%.</RiskModel> |
Latest revision as of 23:25, 4 September 2025
Mother's Age
Age Group | Pregnancy Chance per Cycle | Relative Odds vs. 25-29 |
---|---|---|
20-24 |
0.25 |
1.0 |
25-29 |
0.20 |
1.0 |
30-34 |
0.15 |
0.85 |
35-39 |
0.10 |
0.70 |
40-44 |
0.05 |
0.50 |
The fecundity rates per cycle and odds ratios are averages derived from multiple studies on age-related fertility decline, where base rates were normalized (e.g., averaging reported probabilities like 20-25% for ages 20-24 across sources) and odds ratios calculated relative to the peak fertility group.
- Dunson, D. B., et al. (2002). Changes with age in the level and duration of fertility in the menstrual cycle. Human Reproduction.
- American College of Obstetricians and Gynecologists. (2014). Female age-related fertility decline. Fertility and Sterility.
Father's Age
Age Group | Fecundity Reduction per Cycle | Relative Odds vs. 25-34 |
---|---|---|
20-29 |
0.00 |
1.0 |
30-34 |
0.05 |
0.95 |
35-39 |
0.10 |
0.85 |
40-44 |
0.20 |
0.70 |
45+ |
0.30 |
0.60 |
The fecundity reductions and odds ratios are based on aggregated data from studies, with reductions estimated as proportional decreases (e.g., averaging 5-10% for 35-39 from reported time-to-pregnancy increases) and odds ratios inverted from relative risks for subfertility.
- Khandwala, Y. S., et al. (2020). The age of fathers in the USA and the risk of adverse pregnancy outcomes. Reproductive Biology and Endocrinology.
- du Fossé, N. A., et al. (2023). The impact of paternal age on perinatal outcomes: A systematic review. Human Reproduction Update.
Contraception Methods
Method | Typical Use Failure Rate | Perfect Use Failure Rate |
---|---|---|
No method |
0.85 |
0.85 |
Implant |
0.0005 |
0.0005 |
IUD |
0.008 |
0.002 |
Injectable |
0.04 |
0.003 |
Pill |
0.07 |
0.003 |
Patch |
0.07 |
0.003 |
Ring |
0.07 |
0.003 |
Male condom |
0.13 |
0.02 |
Female condom |
0.21 |
0.05 |
Diaphragm |
0.17 |
0.06 |
Spermicide |
0.21 |
0.18 |
Withdrawal |
0.20 |
0.04 |
No calculations were performed; data is directly from standardized CDC effectiveness rates.
Menstrual Cycle Day
Day Relative to Ovulation | Conception Probability |
---|---|
-5 |
0.05 |
-4 |
0.13 |
-3 |
0.27 |
-2 |
0.30 |
-1 |
0.30 |
0 |
0.30 |
+1 |
0.00 |
No calculations were performed; probabilities are direct averages from the landmark study on conception timing.
Intercourse Frequency
Frequency per Week | Pregnancy Chance per Cycle | Relative Odds vs. <1 Time |
---|---|---|
<1 |
0.10 |
1.0 |
1-2 |
0.15 |
1.50 |
3-4 |
0.20 |
2.00 |
Daily |
0.25 |
2.50 |
Fecundity rates and odds ratios are approximated by averaging reported increases in pregnancy rates from studies (e.g., scaling base 10% for infrequent to 25% for daily based on fertile window coverage).
- Stanford, J. B., et al. (2020). Optimizing natural fertility: A committee opinion. Fertility and Sterility.
- American Society for Reproductive Medicine. (2021). Optimizing natural fertility.
BMI Categories
BMI Range | Fecundity Reduction per Cycle | Relative Odds vs. 18.5-24.9 |
---|---|---|
<18.5 (underweight) |
0.20 |
1.50 |
18.5-24.9 (normal) |
0.00 |
1.0 |
25-29.9 (overweight) |
0.10 |
1.20 |
30-34.9 (obese class I) |
0.20 |
1.50 |
35-39.9 (obese class II) |
0.30 |
1.80 |
>=40 (obese class III) |
0.40 |
2.00 |
Reductions and odds ratios are averaged from meta-analyses, converting reported relative risks for infertility (e.g., 1.2-2.0 for obesity) into proportional fecundity drops.
- Silvestris, E., et al. (2022). Obesity and female fertility: A comprehensive review. Reproductive Biology and Endocrinology.
- Best, D., et al. (2023). The impact of body mass index on female fertility. Human Reproduction.
Smoking Status
Status | Cigarettes per Day | Fecundity Reduction per Cycle | Relative Odds for Infertility |
---|---|---|---|
Nonsmoker |
0 |
0.00 |
1.0 |
Light smoker |
1-10 |
0.10 |
1.30 |
Moderate smoker |
11-20 |
0.20 |
1.60 |
Heavy smoker |
>20 |
0.30 |
2.00 |
Reductions are estimated by averaging dose-response data from reviews, translating odds ratios into percentage fecundity decreases (e.g., OR 1.3 implies ~10% reduction).
Alcohol Consumption
Drinks per Week | Fecundity Reduction per Cycle | Relative Odds vs. Nondrinker |
---|---|---|
None |
0.00 |
1.0 |
1-5 (light) |
0.05 |
1.10 |
6-10 (moderate) |
0.15 |
1.30 |
>10 (heavy) |
0.25 |
1.60 |
Reductions are averaged from dose-response meta-analyses, converting odds ratios for reduced fecundability into proportional decreases (e.g., OR 1.3 ≈ 15% reduction).
- Fan, D., et al. (2017). Female alcohol consumption and fecundability: A systematic review and dose-response meta-analysis. Scientific Reports.
- Eggert, J., et al. (2004). Effects of alcohol consumption on female fertility during an 18-month period. Fertility and Sterility.
RiskModel: Pregnancy/Data:chance_of_getting_pregnant_in_a_month Calculation: (fecundity_per_cycle * odds_ratio_vs_25_29 * odds_ratio_vs_25_34 * (1 / odds_ratio_vs_18_5_24_9) * (1 / odds_ratio_for_infertility) * (1 / (odds_ratio_vs_nondrinker)) * odds_ratio_vs_1_time * (typical_use_failure_rate / 0.85)) * 100 Content: The estimated chance of getting pregnant in a month (per menstrual cycle) is about {result}%.
RiskModel: Pregnancy/Data:chance_of_getting_pregnant_from_one_act_of_intercourse Calculation: (conception_probability * odds_ratio_vs_25_29 * odds_ratio_vs_25_34 * (1 / (odds_ratio_vs_18_5_24_9)) * (1 / (odds_ratio_for_infertility)) * (1 / (odds_ratio_vs_nondrinker)) * (typical_use_failure_rate / 0.85)) * 100 Content: The estimated chance of getting pregnant from one act of intercourse is about {result}%.