RiskofNeverTakingHRT/Data: Difference between revisions
Risk of Never Taking HRT for Menopause / Data |
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== Fracture Risk Data == | == Fracture Risk Data == | ||
< | <riskdata table="FractureRiskTable" columns="label|withHRT|withoutHRT"> | ||
<head> | <head> | ||
! Scenario (for dropdown) | ! Scenario (for dropdown) | ||
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7.1 years – estrogen‑only HRT | 92–113 | 141 | 7.1 years – estrogen‑only HRT | 92–113 | 141 | ||
5.6 years – combined HRT | 79–96 | 111 | 5.6 years – combined HRT | 79–96 | 111 | ||
</ | </riskdata> | ||
*Explanation:* | *Explanation:* | ||
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== Cardiovascular, Stroke, and VTE Risk Data == | == Cardiovascular, Stroke, and VTE Risk Data == | ||
< | <riskdata table="CardiovascularRiskTable" columns="condition|withHRT|withoutHRT"> | ||
<head> | <head> | ||
! Condition (for dropdown) | ! Condition (for dropdown) | ||
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Stroke | 44 | 32 | Stroke | 44 | 32 | ||
Venous thromboembolism (VTE) | 34 | 16 | Venous thromboembolism (VTE) | 34 | 16 | ||
</ | </riskdata> | ||
*Explanation:* | *Explanation:* | ||
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== Cancer Risk Data == | == Cancer Risk Data == | ||
< | <riskdata table="CancerRiskTable" columns="cancerType|withHRT|withoutHRT"> | ||
<head> | <head> | ||
! Cancer Type (for dropdown) | ! Cancer Type (for dropdown) | ||
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Ovarian Cancer | ~1 per 1,000 | baseline varies | Ovarian Cancer | ~1 per 1,000 | baseline varies | ||
Endometrial Cancer (combined HRT) | reduced/neutral | baseline varies | Endometrial Cancer (combined HRT) | reduced/neutral | baseline varies | ||
</ | </riskdata> | ||
*Explanation:* | *Explanation:* | ||
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== Dementia Risk Data == | == Dementia Risk Data == | ||
< | <riskdata table="DementiaRiskTable" columns="scenario|withHRT|withoutHRT"> | ||
<head> | <head> | ||
! Scenario (for dropdown) | ! Scenario (for dropdown) | ||
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</head> | </head> | ||
Women ≥65, combined HRT | 11 | 9 | Women ≥65, combined HRT | 11 | 9 | ||
</ | </riskdata> | ||
*Explanation:* | *Explanation:* |
Latest revision as of 17:34, 12 September 2025
Data for RiskOfNeverTakingHRTForMenopause
Fracture Risk Data
Scenario (for dropdown) | Fractures with HRT (per 1000) | Fractures without HRT (per 1000) |
---|---|---|
7.1 years – estrogen‑only HRT |
92–113 |
141 |
5.6 years – combined HRT |
79–96 |
111 |
- Explanation:*
Women on HRT had fewer fractures than those not taking it—for both estrogen-only and combined regimens. - Source: [PubMed – WHI WHR Study](https://pubmed.ncbi.nlm.nih.gov/28093732/?utm_source=chatgpt.com)
RiskModel: RiskofNeverTakingHRT/Data:FractureRiskModel Content: label = label withHRT = withHRT withoutHRT = withoutHRT
Cardiovascular, Stroke, and VTE Risk Data
Condition (for dropdown) | Incidence with HRT (per 10,000) | Incidence without HRT (per 10,000) |
---|---|---|
Coronary heart disease |
157 |
132 |
Stroke |
44 |
32 |
Venous thromboembolism (VTE) |
34 |
16 |
- Explanation:*
Combined HRT is associated with slightly higher incidence of CHD, stroke, and VTE. - Source: [CMAJ WHI Summary](https://www.cmaj.ca/content/170/10/1535?utm_source=chatgpt.com)
RiskModel: RiskofNeverTakingHRT/Data:CHDRiskModel Content: condition = 'Coronary heart disease' withHRT = withHRT withoutHRT = withoutHRT
RiskModel: RiskofNeverTakingHRT/Data:StrokeRiskModel Content: condition = 'Stroke' withHRT = withHRT withoutHRT = withoutHRT
RiskModel: RiskofNeverTakingHRT/Data:VTERiskModel Content: condition = 'Venous thromboembolism (VTE)' withHRT = withHRT withoutHRT = withoutHRT
Cancer Risk Data
Cancer Type (for dropdown) | Incidence with HRT (per women-years) | Baseline without HRT |
---|---|---|
Breast Cancer (combined HRT) |
+9 to +36 per 10,000 |
baseline varies |
Ovarian Cancer |
~1 per 1,000 |
baseline varies |
Endometrial Cancer (combined HRT) |
reduced/neutral |
baseline varies |
- Explanation:*
Combined HRT may increase breast and ovarian cancer risk, but appears neutral or protective for endometrial cancer. - Sources:
- [Menopause.org.au Breast Cancer](https://www.menopause.org.au/members/ims-menopause-live/use-of-hormone-replacement-therapy-hrt-and-risk-of-breast-cancer?utm_source=chatgpt.com) - [SAGE Journal Analysis](https://journals.sagepub.com/doi/10.1177/2053369120957514?utm_source=chatgpt.com)
RiskModel: RiskofNeverTakingHRT/Data:BreastCancerRiskModel Content: cancerType = 'Breast Cancer (combined HRT)' withHRT = withHRT
RiskModel: RiskofNeverTakingHRT/Data:OvarianCancerRiskModel Content: cancerType = 'Ovarian Cancer' withHRT = withHRT
Dementia Risk Data
Scenario (for dropdown) | Dementia incidence with HRT (per 1000) | Dementia incidence without HRT (per 1000) |
---|---|---|
Women ≥65, combined HRT |
11 |
9 |
- Explanation:*
In women aged 65+, combined HRT is tied to slightly higher dementia risk. - Source: [WHI Memory Study – PubMed](https://pubmed.ncbi.nlm.nih.gov/28093732/?utm_source=chatgpt.com)
RiskModel: RiskofNeverTakingHRT/Data:DementiaRiskModel Content: scenario = 'Women ≥65, combined HRT' withHRT = withHRT withoutHRT = withoutHRT
Uncertainty Note
These figures represent population averages and may not apply to every individual due to variables like geography, age at menopause, HRT type, and personal health.
Generated by an AI assistant.