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Risk of Never Taking HRT for Menopause / Data
m Text replacement - "datatable2" to "riskdata"
 
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== Fracture Risk Data ==
== Fracture Risk Data ==
<datatable2 table="FractureRiskTable" columns="label|withHRT|withoutHRT">
<riskdata table="FractureRiskTable" columns="label|withHRT|withoutHRT">
<head>
<head>
! Scenario (for dropdown)
! Scenario (for dropdown)
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7.1 years – estrogen‑only HRT | 92–113 | 141
7.1 years – estrogen‑only HRT | 92–113 | 141
5.6 years – combined HRT      | 79–96  | 111
5.6 years – combined HRT      | 79–96  | 111
</datatable2>
</riskdata>


*Explanation:*   
*Explanation:*   
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== Cardiovascular, Stroke, and VTE Risk Data ==
== Cardiovascular, Stroke, and VTE Risk Data ==
<datatable2 table="CardiovascularRiskTable" columns="condition|withHRT|withoutHRT">
<riskdata table="CardiovascularRiskTable" columns="condition|withHRT|withoutHRT">
<head>
<head>
! Condition (for dropdown)
! Condition (for dropdown)
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Stroke                          | 44  | 32
Stroke                          | 44  | 32
Venous thromboembolism (VTE)  | 34  | 16
Venous thromboembolism (VTE)  | 34  | 16
</datatable2>
</riskdata>


*Explanation:*   
*Explanation:*   
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== Cancer Risk Data ==
== Cancer Risk Data ==
<datatable2 table="CancerRiskTable" columns="cancerType|withHRT|withoutHRT">
<riskdata table="CancerRiskTable" columns="cancerType|withHRT|withoutHRT">
<head>
<head>
! Cancer Type (for dropdown)
! Cancer Type (for dropdown)
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Ovarian Cancer              | ~1 per 1,000        | baseline varies
Ovarian Cancer              | ~1 per 1,000        | baseline varies
Endometrial Cancer (combined HRT) | reduced/neutral | baseline varies
Endometrial Cancer (combined HRT) | reduced/neutral | baseline varies
</datatable2>
</riskdata>


*Explanation:*   
*Explanation:*   
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== Dementia Risk Data ==
== Dementia Risk Data ==
<datatable2 table="DementiaRiskTable" columns="scenario|withHRT|withoutHRT">
<riskdata table="DementiaRiskTable" columns="scenario|withHRT|withoutHRT">
<head>
<head>
! Scenario (for dropdown)
! Scenario (for dropdown)
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</head>
</head>
Women ≥65, combined HRT | 11 | 9
Women ≥65, combined HRT | 11 | 9
</datatable2>
</riskdata>


*Explanation:*   
*Explanation:*   

Latest revision as of 17:34, 12 September 2025

Data for RiskOfNeverTakingHRTForMenopause

Fracture Risk Data

Scenario (for dropdown) Fractures with HRT (per 1000) Fractures without HRT (per 1000)

7.1 years – estrogen‑only HRT

92–113 
141

5.6 years – combined HRT

79–96  
111
  • Explanation:*

Women on HRT had fewer fractures than those not taking it—for both estrogen-only and combined regimens. - Source: [PubMed – WHI WHR Study](https://pubmed.ncbi.nlm.nih.gov/28093732/?utm_source=chatgpt.com)

  RiskModel: RiskofNeverTakingHRT/Data:FractureRiskModel
    Content: 
label = label
withHRT = withHRT
withoutHRT = withoutHRT

Cardiovascular, Stroke, and VTE Risk Data

Condition (for dropdown) Incidence with HRT (per 10,000) Incidence without HRT (per 10,000)

Coronary heart disease

157 
132

Stroke

44  
32

Venous thromboembolism (VTE)

34  
16
  • Explanation:*

Combined HRT is associated with slightly higher incidence of CHD, stroke, and VTE. - Source: [CMAJ WHI Summary](https://www.cmaj.ca/content/170/10/1535?utm_source=chatgpt.com)

  RiskModel: RiskofNeverTakingHRT/Data:CHDRiskModel
    Content: 
condition = 'Coronary heart disease'
withHRT = withHRT
withoutHRT = withoutHRT

  RiskModel: RiskofNeverTakingHRT/Data:StrokeRiskModel
    Content: 
condition = 'Stroke'
withHRT = withHRT
withoutHRT = withoutHRT

  RiskModel: RiskofNeverTakingHRT/Data:VTERiskModel
    Content: 
condition = 'Venous thromboembolism (VTE)'
withHRT = withHRT
withoutHRT = withoutHRT

Cancer Risk Data

Cancer Type (for dropdown) Incidence with HRT (per women-years) Baseline without HRT

Breast Cancer (combined HRT)

+9 to +36 per 10,000 
baseline varies

Ovarian Cancer

~1 per 1,000         
baseline varies

Endometrial Cancer (combined HRT)

reduced/neutral 
baseline varies
  • Explanation:*

Combined HRT may increase breast and ovarian cancer risk, but appears neutral or protective for endometrial cancer. - Sources:

 - [Menopause.org.au Breast Cancer](https://www.menopause.org.au/members/ims-menopause-live/use-of-hormone-replacement-therapy-hrt-and-risk-of-breast-cancer?utm_source=chatgpt.com)  
 - [SAGE Journal Analysis](https://journals.sagepub.com/doi/10.1177/2053369120957514?utm_source=chatgpt.com)
  RiskModel: RiskofNeverTakingHRT/Data:BreastCancerRiskModel
    Content: 
cancerType = 'Breast Cancer (combined HRT)'
withHRT = withHRT

  RiskModel: RiskofNeverTakingHRT/Data:OvarianCancerRiskModel
    Content: 
cancerType = 'Ovarian Cancer'
withHRT = withHRT

Dementia Risk Data

Scenario (for dropdown) Dementia incidence with HRT (per 1000) Dementia incidence without HRT (per 1000)

Women ≥65, combined HRT

11 
9
  • Explanation:*

In women aged 65+, combined HRT is tied to slightly higher dementia risk. - Source: [WHI Memory Study – PubMed](https://pubmed.ncbi.nlm.nih.gov/28093732/?utm_source=chatgpt.com)

  RiskModel: RiskofNeverTakingHRT/Data:DementiaRiskModel
    Content: 
scenario = 'Women ≥65, combined HRT'
withHRT = withHRT
withoutHRT = withoutHRT

Uncertainty Note

These figures represent population averages and may not apply to every individual due to variables like geography, age at menopause, HRT type, and personal health.

Generated by an AI assistant.