Risk of Never Taking Hormone Replacement Therapy (HRT) During Menopause

Hormone Replacement Therapy (HRT), also known as Menopausal Hormone Therapy (MHT), is used to manage menopausal symptoms and reduce certain long-term health risks. This page helps estimate the **risk associated with not using HRT** — specifically in areas like fracture risk, cardiovascular disease, dementia, and cancer.

Your Inputs

Please answer the questions below to estimate your relative risks if no HRT is taken.

How many years have you gone without HRT? This affects how much exposure your body has had to lower estrogen levels post-menopause, which can increase risks such as bone fracture. <DropDown name="FractureRiskTable">

What is your cardiovascular and blood clot risk without HRT? These outcomes include coronary heart disease, stroke, and venous thromboembolism (VTE). <DropDown name="CardiovascularRiskTable">

What is your estimated cancer risk without HRT? This includes potential increases in breast and ovarian cancer from taking (or not taking) hormone therapy. <DropDown name="CancerRiskTable">

Are you 65 or older and concerned about dementia risk? Some studies show that starting HRT late (after 65) may be linked to increased dementia risk. <DropDown name="DementiaRiskTable">

Your Results

Below are estimated changes in outcomes related to **not taking HRT**:

Fracture Risk Difference

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Cancer Risk Differences

Dementia Risk Difference (Age ≥65)

See the data page for complete data sources, tables, and calculations.

Generated by an AI assistant.